Journal article

Expiratory airflow in late adolescence and early adulthood in individuals born very preterm or with very low birthweight compared with controls born at term or with normal birthweight: a meta-analysis of individual participant data

LW Doyle, S Andersson, A Bush, JLY Cheong, H Clemm, KAI Evensen, A Gough, T Halvorsen, P Hovi, E Kajantie, KJ Lee, L McGarvey, I Narang, P Näsänen-Gilmore, S Steinshamn, M Vollsaeter, EJLE Vrijlandt

Lancet Respiratory Medicine | ELSEVIER SCI LTD | Published : 2019

Abstract

Background: Maximal expiratory airflow peaks early in the third decade of life, then gradually declines with age. The pattern of airflow through adulthood for individuals born very preterm (at <32 weeks' gestation) or with very low birthweight (2499 g) or at term. Methods: We did a meta-analysis of individual participant data from cohort studies, mostly from the pre-surfactant era. Studies were identified through the Adults born Preterm International Collaboration and by searching PubMed and Embase (search date May 25, 2016). Studies were eligible if they reported on expiratory flow rates beyond 16 years of age in individuals born very preterm or with very low birthweight, as well as control..

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